A randomized double-blind placebo-controlled trial.
Scand J Gastroenterol 2002;37:444-449

Based on a preliminary pilot study which suggested efficacy of wheatgrass juice in the treatment of ulcerative colitis (UC). 23 patients diagnosed clinically and sigmoidoscopically with active UC were randomly allocated to receive either 100cc of wheat grass juice, or a matching placebo, daily for 1 month. 21 patients completed the study. Treatment with wheat grass juice was associated with significant reductions in overall disease activity and severity of rectal bleeding. No serious side effects were found. The researchers concluded that wheat grass juice has a therapeutic role and offers a genuine therapeutic advantage in patients with active left colon ulcerative colitis. Notable was the potential of patients being empowered by producing their own wheatgrass thereby becoming active participants in their own treatment.